Zimin S. Experimental substantination of application of the new topical combined cream-gel in joint diseases

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0417U000431

Applicant for

Specialization

  • 14.03.05 - Фармакологія

10-02-2017

Specialized Academic Board

Д 64.605.03

National University of Pharmacy

Essay

The dissertation work of devoted to experimental substantiation of application of combined cream-gel of glucosamine hydrochloride with chondroitin sulfate with camphor and menthol to optimize drug therapy of osteoarthritis. The optimal ratio of glucosamine hydrochloride and chondroitin sulfate 1: 1 in topical dosage form of a cream-gel, which causes expressed analgesic, antialterative, antiexudative moderate antiproliferative activity. Using light and electron microscopy proved a strong chondroprotective effect researched combination in the model of systemic steroid arthritis in rats and noted its positive impact on the content of biochemical parameters of connective tissue metabolism

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