The thesis is devoted to studying the nature of the interaction typological characteristics of higher nervous activity and protein metabolism in pigs for the actions of technological stress. Researched typological characteristics of higher nervous activity in pigs. It was established that the average cortical processes in animals strong balanced mobile type is 3.87±0.08, higher at 15.6 % (p<0.01), 32.2 % (p<0.001) and 3.2 times (p<0.001) than in animals inert strong balanced, strong and weak unbalanced types of higher nervous activity. The thesis highlights the issue of sharing features of protein in pigs of different types of higher nervous activity. In particular, it was found that in animals of the weak type of higher nervous activity content of total protein in serum of below 6.6 % (p<0.01), albumin 11.7 % (p<0.01), urea 13,2 % (p<0.001), lysine, methionine and threonine 6.9 % (p<0.05), 12.6 (p<0.05) and 19.1 % (p<0.05), respectively to that of animals strong balanced mobile type of higher nervous activity For the first time the peculiarities of protein metabolism in pigs of different types of higher nervous activity under the influence of technological stress. During the process of stress decreases total protein content (by 11–21 %; p<0.001), albumin (15–25 %, p<0.001), ?-globulins (by 13–38 %; p<0.05–0.001) increases the urea content (in 1.23–1.72 times; p?0.001) and transaminase activity (in 1.2–1.5 times; p<0.001) in the serum of animals of different types of higher nervous activity. Investigated the relationship between individual characteristics of higher nervous activity and metabolism of proteins in terms of correlation, variance and regression analysis. Established functional connections strength, balance and mobility cortical processes of technological stimulus to action containing albumin, urea (r=0.56–0.80; p?0,01–0,001), 2-globulin (r=-0.49, p<0.05), and after the technological stimulus to total protein content (r=0.62–0.79; p<0.01–0.001), urea 25 (r=-0.40–0.51; p<0.05), globulin (r=0.62–0.89; p<0.01–0.001), ALT (r=-0.71–0.79; p<0.001) and AST (r=-0.22–0.44; p?0.05). The strength of the technological processes of cortical stress has significant effect on the content of total protein, albumin, urea and aspartate aminotransferase activity in serum of pigs (2 x=0.29–0.41, p<0.05–0.01), and after the process steps stimulus to the content of total protein, globulin, gamma globulin, urea and activity of enzymes in the serum of animals (2 x=0.22–0.77, p<0.05–0.001).