Mandygra U. Sanitary assessment of application of disinfectants on the basis of polyhexamethyleneguanidine in livestock breeding.

The results of the development of the use and the sanitary assessment of the disinfectants "Epidez" and "Epidez-barrier" in animal husbandry have been presented in the thesis. The above disinfectants were developed on the basis of the synthesized polyhexamethyleneguanidine (PHMH). It has been found out that the working solutions of DS "Epidez" do not have corrosive action on metals, do not cause irritating action on mucous membranes and LD50 is 5 907.5 mg/kg that proves that the drug belongs to low toxic substances. The disinfectant is applied by finely dispersed spraying method or by wet wiping. After drying of the solution a thin, transparent polymer layer is formed on the treated surface which provides for an extended antiseptic action. The drug has high microbocidic properties. The production tests of the efficiency of solutions of the disinfectants "Epidez" and "Epidez-barrier" have been conducted on the dairy farms and meat processing plants and they have shown an absolute bactericidal effect on the E.coli, bacilli and clostridia. The calculations of the economic efficiency have proved that the disinfection of the bed of the pans by the working solutions of the "Epidezus" is 17.6 times cheaper, in the livestock buildings - 13.3 times and the equipment of meat processing enterprises - 7.3 times cheaper as compared with the preparations of the similar action under the Price List for veterinary services.