As a result of the experimental investigations the hygienic assessment of the influence of the technological factors – the systems of housing, lighting and noise as well as psoroptosis invasion on the status of the immunity and productivity of domestic rabbits have been presented in the thesis. The sanitary and hygienic substantiation of the expediency of the application of the probiotic «Evitalia» as a preparation to improve non-specific resistance, durability, the growth intensity of the rabbits and the quality of their products have been done.
It has been established that the parameters of microclimate in the outer rabbit hutches were in accordance with the sanitary and hygienic requirements: the content of harmful gases, bacterial contamination, the relative humidity of the air was lower and the lighting was higher as compared to the sheds.
The optimal parameters of microclimate in the outer hutches in comparison with the sheds stimulated the increase in the nonspecific resistance of the rabbits. The parameters of BABS, LABS, PhAN, the content of B-lymphocytes, the total content of immunoglobulins were trustworthy higher.
The use of the light intensity of 70-75 and 90-95 lx stimulated the increase in the content of total protein including albumins and γ-globulins in the blood serum of the rabbits. The production noise of the intensity 40-45 and 90-95 decibels that was produced by the work of the technological equipment depressed the state of the natural immunity; it was proved by the decrease in its parameters. Noise as a stress factor did not have any influence on the content of the lacto trope hormone but it stimulated the increase in the content of progesterone and estradiol in the blood serum of the doe rabbits. As a result of the long-term influence of the noise such reproductive performances of the doe rabbits as impregnation, multiple birth, milk yield and the duration of the descendants were lower. The volume of the ejaculate in the bucks was nearly the same but the concentration of the sperm, the sperm motility, resistance and dehydrogenase activity were trustworthy lower.
When the young of the rabbits was invaded by the causative agent of psoroptosis there was the decrease in the content of hemoglobin and erythrocytes, the increase in the content of leucocytes in the blood, there was the decrease in the content of the total protein, BABS, LABS, relative content of T- and B-lymphocytes in the blood serum.
The use of the probiotic preparation «Evitalia» stimulated the state of the natural immunity in the young of the rabbits that was proved by the increase in the content of hemoglobin, erythrocytes, leucocytes, BABS, LABS, PhI and PhAN in the animals.
The use of the probiotic «Evitalia» for the young of the rabbits stimulated the increase in their live weight, protein and quality index of the rabbit meat. The profitability of the application of the probiotic «Evitalia» was 2,86 hrv.