Yer'omenko R. The exsperimental substantiation of development of the new medicinal form on basis Loratadine for treatment allergic rhinits and dermatitis.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0499U002425

Applicant for

Specialization

  • 14.03.05 - Фармакологія

14-10-1999

Specialized Academic Board

Д 26.550.01

Institute of Pharmacology and Toxicology of the National Academy of Medical Sciences of Ukraine

Essay

The pharmacokinetical and pharmacological research of the new medicinal form for dermatology and otolaringology antiallergic of action - Loratadine is conducted. Gel with Loratadine have expressed antiallergic, antiinflammatory and antihistaminic action. Transdermal and nasalis gels with Loratadine havt a high degree of bioavailability and local simptomatical by effect and simultaneously render therapy - profilactic effect through general circulation. Transdermal and nasalis of a way of introduction Loratadine are more effective in comparison with ultragastric.

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