Erstenyuk A. Biochemical mechanisms of the erythrocytes damage in the conditions of experimental cadmium intoxication

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0505U000097

Thesis Registration Form

0505U000097.pdf

Applicant for

Specialization

  • 14.01.32 - Медична біохімія

03-02-2005

Specialized Academic Board

Д 26.003.07

Essay

It has been shown that the development of combined hemic and tissue hypoxia under the influence of cadmium ions leads to the disorders of histostructure and ultrastructure of the inner organs. Morphologic changes of the liver tissues manifested themselves by ruining of membrane structures, proteinsynthesizing, energy and hereditary apparatuses of the hepatocytes, by the disorders of filtration and reabsorption parts of the kidneys. Conceptual model of the primary biochemical mechanisms of the damaging effect of cadmium ions been created. The use of pharmacological preparations of antioxidant action (Unitiol, Selenium) has been substantiated for the correction of metabolism disturbances resulted from cadmium intoxication.

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Files

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