Divocha V. The Biologic-Virological Ground of Antiproteinase Therapy of Influenza.

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0509U000210

Thesis Registration Form

0509U000210.pdf

Applicant for

Specialization

  • 14.01.32 - Медична біохімія

05-03-2009

Specialized Academic Board

Д 26.003.07

Essay

Dissertation is devoted to the questions of estimation of interaction of the protelytic system of host cell with the influenza virus multiplying inside of it. A new direction in virology is developed in the work. This direction is based on complex estimation of the use of cellular enzymes and their inhibitors: specific antiproteinase immune sera, and inhibitors of trypsin-like proteinases, which are able to block the development of influenza infection in intercellular space or inside of the cell while viral morphogenesis. There has been shown: blocking properties of trypsin-like proteinases inhibitor isolated from the lungs of healthy mice and neutralizing features of rat antiproteinase immune sera that was produced against the third isoenzyme of trypsin-like protease got from the lungs of healthy mice. There has been: method of obtaining of trypsin-like proteinases inhibitor and using it as a preparation for influenza treatment; method of treatment of the influenza in experiment; method of determination of the organism's defenses in the experiment. The basic results of the thesis found application at the creation of antiviral preparation.

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Files

AREF.doc

Текст дис Дівоча--Введение.doc

Текст дис Дівоча--Выводы.doc

Текст дис Дівоча--Литература.doc

Текст дис Дівоча--Раздел 1.doc

Текст дис Дівоча--Раздел 2.doc

Текст дис Дівоча--Раздел 3.doc

Текст дис Дівоча--Раздел 4.doc

Текст дис Дівоча--Раздел 5.doc

Текст дис Дівоча--Раздел 6.doc

Текст дис Дівоча--Раздел 7.doc

Текст дис Дівоча--Раздел 8.doc

Текст дис Дівоча--Раздел 9.doc

Текст дис Дівоча--Содержание.doc

Текст дис Дівоча--Титульный лист.doc

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