Shevchenko L. Scientific substantiation of carotenoides application in the system of prevention of functional disorders in livestock

Scientific principles of carotenoides application in the system of prevention of functional disorders and reproductive performance stimulation in livestock have been explained. Relations between biological activity of carotenoides in the body and its form, dose and regime of application as well as the animal species, age, performance type and physiological condition have been revealed. Species related peculiarities in assimilation of Bl. trispora TKST strain ?-carotene and xanthophylls in laboratory and farm animals have been detected. Understanding of carotene metabolical transformations in poultry, swine and cattle has been extended and completed, based on ability of trans-?-carotene of Bl. trispora fungi to be transformed into vitamin A, accumulate in the tissues and products, stimulate reproductive performance and youngstock growth and development. Obtained results on ?-carotene biological action on the animal body complement existing concept of independent role of carotenoides in the processes of immune competent cells proliferation and specialization, exchange of different lipids classes and vitamin A in the tissues, which can be used in development of preventative and therapeutical treatments of non-infectious disorders. Scientific and practical recommendations on the use of ?-carotene from biotechnological synthesis for improvement of livestock reproduction and performance have been developed.