Sokolova L. The theoretical and experimental foundation of obtaining technology of phytosubstances by lyophilization

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0512U000536

Applicant for

Specialization

  • 15.00.01 - Технологія ліків, організація фармацевтичної справи та судова фармація

06-06-2012

Specialized Academic Board

Д 64.605.02

National University of Pharmacy

Essay

First time the theoretical and experimental foundation of obtaining technology of phytosubstances by lyophilization to prevent the process of aging (anti aging). It has been found the regularities of the influence of various physico-chemical and technological factors (freezing temperature, dilution of fruit juices, the character and quantity of structure-creators) on crystallographic and pharmacotechnological indicators, humidity, moisture absorption of freeze dried powders, the yield of the loads, which allow predicting and scientifically justifying the technology of freeze-drying powders of plant material. The industrial technology and quality control methods are investigated; stability during its storage and biological activity of phytosubstances are studied, the appropriate regulatory and technical documentation is approved

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