Object of research: morphology and function of organs of reproductive (ovaries) and endocrine (pituitary, thyroid and adrenal glands) sheep and goats, their placentas, embryos and fetuses, newborn lambs and kids; mechanisms of alimentary infertility in sheep and goats, and assessment of the embryo / fetus and newborn animals, diagnosis, therapy and prevention of reproductive disorders in sheep and goats caused by a deficiency of vitamin A, their therapeutic and cost-effectiveness. Objective: to determine the morphological structure and function of the reproductive organs and the endocrine system of sheep and goats in vitamin A, development and validation of methods of diagnosis, treatment and prevention of reproductive disorders and perinatal pathology. Research methods: clinical (inspection, palpation, diagnostic slaughter), morphological (macro- and microstructure of the embryos / fetuses and their bodies); placentas, organs of endocrine (pituitary, thyroid and adrenal glands) and reproductive (ovaries) systems, biochemical (determination of individual hemostatic - the quantity of erythrocytes, hemoglobin, total protein, total calcium, inorganic phosphorus, vitamin A, zinc, copper, cobalt, an alkali reserve) special (ultrasound and determination of hormones), the statistical use of information technology (computer programs), a biometric processing digital data. Scientific novelty: for the first time comprehensively defined morphology and function of organs of endocrine and reproductive, feto-placental complex sheep and goat, embryos / fetuses, newborn lambs and kids to deficiency of vitamin A, to develop objective methods for predicting the course of labor in sheep and goats, and evaluation of the embryo / fetus, the clinical condition of newborn lambs and kids and their development potential, a comprehensive diagnosis of nutritional infertility in sheep and goats caused by a lack of vitamin A, an effective program offered the treatment lambs and kids from the prenatal malnutrition, reproductive disorders in sheep and goats caused by a deficiency of vitamin A, scientifically sound method of comprehensive prevention perinatal disease in sheep and goats caused by a deficiency of vitamin A, is defined therapeutic and cost-effective way to the treatment and prevention of reproductive disorders in sheep and goats caused by a deficiency of vitamin A, obtained declarative patent for an invention (№ 7108 "Method for the treatment of sheep and goats with hypogonadismus from 10.07.2012). The level of introduction of scientific research results are implemented in farms with different forms of ownership of central, eastern and southern regions of Ukraine. Area of use: animal husbandry, veterinary medicine.