Maslak G. Glycoforms of plasma proteins and cells and gene expression in leukemias

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0516U000816

Thesis Registration Form

0516U000816.pdf

Applicant for

Specialization

  • 14.01.32 - Медична біохімія

07-10-2016

Specialized Academic Board

Д 29.600.03

Essay

Dissertation is devoted to identify common patterns of changes in oligosaccharide structures of glycoconjugates and circadial gene expression, glycosidases/glycosyltransferases, fibronectin and its receptor gene expression in leukemic diseases. There was decreasing amount of glycoforms with terminal ?2,3-linked sialic acids of plasma ?1-acid glycoprotein and fibronectin in myeloproliferative neoplasms, increasing level of glycoforms ?1-acid glycoprotein that fibronectin, branched and abbreviated N-glycans in B-chronic lymphocytic leukemia.

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Files

aref1.doc

dis.doc

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