Telyatnikov A. Use of nanoparticles of Mg, Fe, Co, Cu, Zn, Ag at fractures of bones and their complications in dogs

Object of research - fractures of bones of extremities in dogs and their complication. Aim of research - clinically-experimentally to prove methods of using of composites of nanoaquakhelats of metals Mg, Fe, Co, Cu, Zn, Ag for treatment of bones fractures and their complications in dogs. Methods of researches - clinical, computer-tomographical, radiological, morphometrical, X-ray densitometrical, hematological, biochemical, immunological, histological, histochemical, bacteriological and statistical. Scientific novelty. Morphometrical and physical features of radius and tibial bones of dogs in normal conditions and in various types of injuries were found. Harmlessness and safety of composites of nanoaquakhelats of metals was proved. Features of systemic influence of composites of nanoaquakhelats of metals at model fractures of a femur in rats and the character of their influence to the healing of fractures are investigated. Positive dynamic of current of osteoreparation of the closed fractures of bones in dogs with using of composites of nanoaquakhelats of metals in various methods of osteosynthes and ways of its application due to strengthening of bone tissue density, increase in protein- synthesizing function of liver and nonspecific immunological reactivity was found. Researches of wound exudate microflora in open fractures of bones in dogs were made and methods of treatment with composites of nanoaquakhelats of metals of a purulent osteomyelitis of various etiology were improved. It is introduced: materials of the thesis were included into the handbook and methodical recommendations, which are used in research and educational work at faculties of higher educational institutions III-IV levels of accreditation. Sphere (area) of use: veterinary medicine